Digami study results

DIGAMI 2: Results and Questions - Medscape

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The DIGAMI 2 study was an international (48-center) trial involving 3000 subjects with a trial design similar to that of DIGAMI 1, enrolling persons with known diabetes or with initial glucose ...

DIGAMI 2: Results and Questions - Medscape

A Review of the DIGAMI Study: Intensive Insulin Therapy ...

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Also, the DIGAMI population, though modest in size, was larger than had been examined before. To place the DIGAMI results in perspective, it is important to note the decrease in overall mortality in diabetic patients with MI in all treatment groups. The DIGAMI study showed overall 1-year post-MI mortality to be 22.4%.

A Review of the DIGAMI Study: Intensive Insulin Therapy ...

The DIGAMI trial: Insulin-glucose infusion in diabetics ...

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Study Rundown: At the time of the DIGAMI study (1995), diabetic patients were shown to have higher mortality rates post-myocardial infarction (MI) than non-diabetic patients. This difference remained despite the introduction of new therapeutic measures, such as beta-blockers. Increased fatty acid ...

The DIGAMI trial: Insulin-glucose infusion in diabetics ...

Randomized trial of insulin-glucose infusion followed by ...

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Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 year. Malmberg K(1), Rydén L, Efendic S, Herlitz J, Nicol P, Waldenström A, Wedel H, Welin L.

Randomized trial of insulin-glucose infusion followed by ...

Mortality prediction in diabetic patients with myocardial ...

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2.1 Study design. A detailed description of DIGAMI including study design, definitions and methods has been given elsewhere . Briefly, this is a multicentre, randomised, prospective study on the effect on mortality and morbidity of an intravenous infusion of insulin–glucose followed by 4-dose subcutaneous insulin therapy given to patients ...

Mortality prediction in diabetic patients with myocardial ...

Cost-effectiveness of intense insulin treatment after ...

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5/1/2000 · Conclusion The results of the DIGAMI study indicate that intense insulin treatment after an acute myocardial infarction in patients with diabetes mellitus has an acceptable level of cost-effectiveness. Myocardial infarction, diabetes mellitus, survival, cost-effectiveness, insulin. f1.

Cost-effectiveness of intense insulin treatment after ...

20 Years On: DIGAMI-1 Informs on Post-MI Insulin in Diabetics

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These results, from a 20-year follow-up of patients in the Diabetes Mellitus Insulin Glucose Infusion in Acute Myocardial Infarction (DIGAMI 1) trial, were published online May 13 in Lancet ...

20 Years On: DIGAMI-1 Informs on Post-MI Insulin in Diabetics

www.ncbi.nlm.nih.gov

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www.ncbi.nlm.nih.gov

Prospective randomised study of intensive insulin ...

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5/24/1997 · Study design. A detailed description of the diabetes mellitus, insulin glucose infusion in acute myocardial infarction (DIGAMI) study, including design, definitions, and methods, has been given elsewhere.15 16 All patients admitted to the coronary care units of 19 Swedish hospitals were considered for inclusion if they had had an acute myocardial infarction within the preceding 24 hours ...

Prospective randomised study of intensive insulin ...

DIGAMI TRIAL PDF - bbppi.info

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The DIGAMI study compared “conventional” anti-diabetic therapy to intensive insulin therapy consisting of acute insulin infusion during the early hours of MI and. ... A final point to emphasize in reviewing the DIGAMI results is the significant mortality reduction noted in patients who were never previously on insulin trizl who had low ...

DIGAMI TRIAL PDF - bbppi.info

Cost-effectiveness of intense insulin treatment after ...

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Request PDF on ResearchGate | Cost-effectiveness of intense insulin treatment after acute myocardial infarction in patients with diabetes mellitus - Results from the DIGAMI study | The aim of the ...

Cost-effectiveness of intense insulin treatment after ...

DIGAMI 2 trial post hoc analysis: Lessons in ...

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12/17/2008 · In their post hoc analysis of the DIGAMI 2 (Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction 2) study, Mellbin and colleagues suggest that insulin therapy after myocardial infarction (MI) may be associated with increased clinical events (not mortality), whereas metformin therapy may be associated with reduced events and sulfonylurea therapy with neutral effects.

DIGAMI 2 trial post hoc analysis: Lessons in ...

Effects of Intensive Glucose Lowering in Type 2 Diabetes ...

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Regardless of the results of these other trials, our study has identified a previously unrecognized harm of intensive glucose lowering in high-risk patients with type 2 diabetes mellitus and high ...

Effects of Intensive Glucose Lowering in Type 2 Diabetes ...

Admission Hyperglycemia and Acute Myocardial Infarction ...

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DIGAMI-2 and HI-5 trial. While the DIGAMI study was able to demonstrate a decrease in both mortality and mean 24-hour blood glucose levels, the DIGAMI-2 and HI-5 studies showed no such significant decrease (Figure 2)[27– 29]. Importantly, the varying glucose target levels of these studies make it difficult to compare their results and infer a

Admission Hyperglycemia and Acute Myocardial Infarction ...

The Hyperglycemia: Intensive Insulin Infusion In ...

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The Hyperglycemia: Intensive Insulin Infusion In Infarction (HI-5) Study ... target in the DIGAMI study (1). Dextrose was included in the protocol as it was a ... cantly alter the results. Statistics Statistical analysis was conducted with the program SPSS. Categorical variables

The Hyperglycemia: Intensive Insulin Infusion In ...

DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in ...

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Prospective randomised study of intensive treatment on long term survival after myocardial infarction in patients with diabetes mellitus: DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in ...

DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in ...

Effect of a Multifactorial Intervention on Mortality in ...

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results of the Steno-2 Study. This education took place both at regional and at national levels.14,15 This report includes follow-up data obtained from September 1, 2006, to December 31, 2006. At fol-

Effect of a Multifactorial Intervention on Mortality in ...

DIGAMI TRIAL PDF - rupertmallin.info

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DIGAMI TRIAL PDF - The DIGAMI study compared "conventional" anti-diabetic therapy to intensive insulin therapy consisting of acute insulin infusion during the early hours of. ... Summary of Results Group characteristics The control group and the infusion group had similar demographics and pre-hospitalization characteristics.

DIGAMI TRIAL PDF - rupertmallin.info

Randomized trial of insulin-glucose infusion followed by ...

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The DIGAMI study (Diabetes Mellitus Insulin-Glucose Infusion in Acute Myocardial Infarction) was initiated to test the hypothesis that rapid improvement of metabolic control in diabetic patients with acute myocardial infarction by means of insulin-glucose infusion decreases the high initial mortality

Randomized trial of insulin-glucose infusion followed by ...

New Insulin Infusion Protocol Improves Blood Glucose ...

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Patients in the study group attained goal blood glucose levels and were stable on an algorithm much more quickly than the control group. The mean time to stabilize for the critical care patients was 3.5 ± 0.3 hours for the study group compared to 9.2 ± 1.1 hours for the control group (p <.0001).

New Insulin Infusion Protocol Improves Blood Glucose ...

Glycometabolic State at Admission: Important Risk Marker ...

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Klas Malmberg, Anna Norhammar, Hans Wedel and Lars Rydén in Acute Myocardial Infarction (DIGAMI) Study Infarction : Long-Term Results From the Diabetes and Insulin-Glucose Infusion Conventionally Treated Patients With Diabetes Mellitus and Acute Myocardial Glycometabolic State at Admission: Important Risk Marker of Mortality in

Glycometabolic State at Admission: Important Risk Marker ...

Journal of the American College of Cardiology

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7/1/1995 · Objectives. We tested how insulin-glucose infusion followed by multidose insulin treatment in diabetic patients with acute myocardial infarction affected mortality during the subsequent 12 months of follow-up. Background. Despite significant improvements in acute coronary care, diabetic patients with acute myocardial infarction still have a high mortality rate.

Journal of the American College of Cardiology

Randomized trial of insulin-glucose ... - ScienceDirect.com

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A reinfarction was defined as an event fulfilling the criteria given for a myocardial infarction but appearing >72 h after the index infarction. Study design. In the multicenter DIGAMI study all pa- tients admitted to the coronary care units of 19 Swedish hospitals (see Appendix) were considered for inclusion.

Randomized trial of insulin-glucose ... - ScienceDirect.com

Implications of the United Kingdom Prospective Diabetes ...

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With this background, we now have the results of the largest and longest study on type 2 diabetic patients that has ever been performed (7,8,9,10). The United Kingdom Prospective Diabetes Study (UKPDS) recruited 5,102 patients with newly diagnosed type 2 diabetes in 23 centers within the U.K. between 1977 and 1991.

Implications of the United Kingdom Prospective Diabetes ...

Glycaemic control after myocardial infarction: The DIGAMI ...

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The subsequent DIGAMI 2 study (Malmberg et al, 2005) sought to answer queries raised by the original study but was also controversial. It is important to note, however, that the DIGAMI study did identify the benefit of strict glycaemic control in patients with AMI.

Glycaemic control after myocardial infarction: The DIGAMI ...

DIGAMI 2—disappointment but not despair - McCallum - 2005 ...

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You have free access to this content DIGAMI 2—disappointment but not despair

DIGAMI 2—disappointment but not despair - McCallum - 2005 ...
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