Cakut epidemiology study

Incidence and Risks of Congenital Anomalies of Kidney and ...

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2/8/2016 · Congenital anomalies of the kidney and urinary tract (CAKUT) are 1 of the major factors in young adults needing renal replacement therapy, but there is little extensive assessment of their incidence and risk factors. This study aimed to evaluate trends in …

Incidence and Risks of Congenital Anomalies of Kidney and ...

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Congenital anomalies of the kidney and urinary tract (CAKUT) constitute approximately 20 to 30 percent of all anomalies identified in the prenatal period . Defects can be bilateral or unilateral, and different defects often coexist in an individual child. An overview of CAKUT is presented here.

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Epidemiology of chronic kidney disease in children

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6/29/2011 · In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available epidemiological data stem from end-stage renal disease (ESRD) registries and information on the earlier stages of pediatric CKD is still limited.

Epidemiology of chronic kidney disease in children

(PDF) Incidence and Risks of Congenital Anomalies of ...

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PDF | Congenital anomalies of the kidney and urinary tract (CAKUT) are 1 of the major factors in young adults needing renal replacement therapy, but there is little extensive assessment of their ...

(PDF) Incidence and Risks of Congenital Anomalies of ...

Epidemiology of chronic kidney disease in children

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Epidemiology of chronic kidney disease in children Jérôme Harambat & Karlijn J. van Stralen & Jon Jin Kim & E. Jane Tizard ... (CAKUT) and hereditary nephropathies, are responsible for about two ... ItalKid Project, a prospective, population-based Italian study on CKD epidemiology, and the North American Pediatric Renal Trials and ...

Epidemiology of chronic kidney disease in children

Recessive mutations in CAKUT and VACTERL association

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that CAKUT is the disease of ‘‘hundreds of genes’’, point mutations in the three genes most commonly associated with thisdisease, HNF1B, PAX2 , andDSTYK, are identified in 10–15% of patients with developmental diseases of the kidney and urinary tract.7,9 Given the epidemiology of CAKUT, recessive genes are likely to be even rarer,

Recessive mutations in CAKUT and VACTERL association

Maternal Diabetes Mellitus and Congenital Anomalies of the ...

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Background: Congenital anomalies of the kidney and urinary tract (CAKUT) are the primary cause of chronic kidney disease in children. The relevance of timing of diabetes mellitus (DM) exposure on risk of CAKUT in exposed children is unknown. Study Design: Population-based nested case-control study.

Maternal Diabetes Mellitus and Congenital Anomalies of the ...

Paediatric end-stage renal disease in a tertiary hospital ...

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2/3/2014 · Children and adolescents with end-stage renal disease (ESRD) in sub-Saharan Africa may have the worst outcomes globally. Barriers to management include late presentation, poor socioeconomic conditions, absence of medical insurance, limited diagnostic facilities and non-availability of chronic renal replacement therapy (RRT). Our study was to determine the incidence, aetiology, management and ...

Paediatric end-stage renal disease in a tertiary hospital ...

Maternal Diabetes Mellitus and Congenital Anomalies of the ...

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Maternal Diabetes Mellitus and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) in the Child ... There were 945 infants identified with CAKUT during the study period who were eligible for inclusion. ... Epidemiology, 11 (6) (2000), pp. 689-694.

Maternal Diabetes Mellitus and Congenital Anomalies of the ...

Congenital anomalies of kidney and urinary tract (CAKUT ...

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1. Epidemiology. Congenital anomalies of the kidney and urinary tract (CAKUT) is the leading cause of end-stage kidney disease (ESKD) in children. 1 It not only places a significant economic burden on health care system but CKD resulting from CAKUT is associated with accelerated cardiovascular disease, resulting in a serious risk of cardiovascular events at young adult age. 2 CAKUT represent ...

Congenital anomalies of kidney and urinary tract (CAKUT ...

EPIDEMIOLOGY AND CLINICAL EVOLUTION OF CONGENITAL ...

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EPIDEMIOLOGY AND CLINICAL EVOLUTION OF CONGENITAL ANOMALIES OF THE KIDNEY AND URINARY TRACT. Article ... The prevalence of children with …

EPIDEMIOLOGY AND CLINICAL EVOLUTION OF CONGENITAL ...

Maternal Diabetes Mellitus and Congenital Anomalies of the ...

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The findings of this study suggest that pregestational DM may affect renal organogenesis and should be considered a clinical risk factor. Because CAKUT is a rare disease, the …

Maternal Diabetes Mellitus and Congenital Anomalies of the ...

Epidemiology of chronic kidney disease in children in ...

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11/3/2011 · Epidemiology of paediatric CKD in Serbia is similar to that reported from developed European countries. The knowledge of the epidemiology of earlier stages of CKD is essential for both institution of renoprotective therapy and planning of RRT, a fact of paramount importance in …

Epidemiology of chronic kidney disease in children in ...

Hirschsprung Disease and Congenital Anomalies of the ...

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Patients with HSCR and CAKUT (isolated or in association) were analyzed for mutations and for susceptibility haplotypes of the whole RET gene. A screening study was also performed on selected GDNF and GFRα-1 exons (see below). Genomic DNA was extracted from peripheral blood using Puregene DNA Isolation Kit (Gentra Systems, Inc, Minneapolis, MN).

Hirschsprung Disease and Congenital Anomalies of the ...

The prevalence and epidemiology of genetic renal disease ...

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6/30/2014 · There are an established and growing number of Mendelian genetic causes for chronic kidney disease (CKD) in adults, though estimates of prevalence have been speculative. The CKD Queensland (CKD.QLD) registry enables partial clarification of this through the study of adults with CKD receiving nephrology care throughout Queensland, Australia.

The prevalence and epidemiology of genetic renal disease ...

Congenital anomalies of kidney and urinary tract ...

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5/1/2013 · The objectives of this study are to determine whether CAKUT occur in familial patterns and to identify if phenotypical variability of renal malformations exists in affected families. Methods: The medical files of CAKUT patients were retrospectively reviewed, and renal and urinary tract abnormalities were recorded for all affected relatives.

Congenital anomalies of kidney and urinary tract ...

Severe congenital anomalies of the kidney and urinary ...

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7/28/2016 · Severe congenital anomalies of the kidney and urinary tract: epidemiology can inform ethical decision-making. ... Retrospective cohort study of severe cases of CAKUT over 14 years.

Severe congenital anomalies of the kidney and urinary ...

Renal outcome in patients with congenital anomalies of the ...

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(CAKUT) are a major cause of morbidity in children. We measured the risk of progression to end-stage renal disease in 312 patients with CAKUT preselected for the presence of anomalies in kidney number or size. A model of dialysis-free survival from birth was established as a function of the renal

Renal outcome in patients with congenital anomalies of the ...

MDCT and MR Urogram Spectrum of Congenital Anomalies of ...

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OBJECTIVE. Congenital anomalies of the kidneys and urinary tract (CAKUT) encompass a spectrum of anomalies that result from genetic, epigenetic, environmental, and molecular signal aberrations at key stages of urinary tract development. CAKUT can be seen incidentally on cross-sectional imaging of the abdomen or can be a cause for adult-onset chronic kidney disease, posing new challenges for ...

MDCT and MR Urogram Spectrum of Congenital Anomalies of ...

Involvement of the bone morphogenic protein/SMAD signaling ...

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12/2/2017 · Congenital anomalies of the kidney and urinary tract (CAKUT), such as renal dysplasia, hydronephrosis, or vesicoureteral reflux, are the most common causes of end-stage renal disease. However, the genetic etiology of CAKUT remains unclear. In this study, we performed whole exome sequencing (WES) to elucidate the genetic etiology of symptomatic CAKUT and CAKUT accompanied …

Involvement of the bone morphogenic protein/SMAD signaling ...

The copy number variation landscape of congenital ...

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12/21/2018 · Congenital anomalies of the kidney and urinary tract (CAKUT) are a major cause of pediatric kidney failure. We performed a genome-wide analysis of …

The copy number variation landscape of congenital ...

History of Childhood Kidney Disease and Risk of Adult End ...

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Study Participants. We conducted a historical cohort study of Israeli adolescents. Our study included potential army recruits who had a mean age of 17.7 years (range, 16 to 25) at the initial ...

History of Childhood Kidney Disease and Risk of Adult End ...

End-stage renal disease in Slovak children: epidemiology ...

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This study presents an overview of the epidemiology and etiology of ESRD and RRT in Slovak children, focusing on Table 3 Etiology of ESRD in new patients (cohort 2003–2009) changes observed in the period 2003–2009 compared to Etiology Total Gender historical data …

End-stage renal disease in Slovak children: epidemiology ...

Clinical importance of pyelocalyceal dilation diagnosed by ...

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Similar to our study, Coelho et al. which is in accordance with the indings of Ilić et al. (2011), (2007), Tsai et al. (1998), and Grazioli et al. (2010) showed who found an equal prevalence of UTI in both sexes in the that the percentage of associated CAKUT positively correlat- irst 2 years of life [28].

Clinical importance of pyelocalyceal dilation diagnosed by ...

Epidemiology of chronic kidney disease in children ...

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For example, the ItalKid Project, a prospective, population-based Italian study on CKD epidemiology, and the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS), defined CKD as having a glomerular filtration rate (GFR) of below 75 ml/min/1.73 m2 [5, 6].

Epidemiology of chronic kidney disease in children ...

An epidemiological study of Hirschsprung's disease and ...

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An epidemiological study of Hirschsprung's disease and additional anomalies. ... Chin-Li Lu, Shew-Meei Sheu, Hsing-Ching Kuo, Epidemiology of Hirschsprung's Disease in Taiwanese Children: A 13-year Nationwide ... Prem Puri, Congenital anomalies of the kidney and urinary tract (CAKUT) associated with Hirschsprung’s disease: a ...

An epidemiological study of Hirschsprung's disease and ...

Early detection of congenital anomalies of the kidney and ...

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5/1/2018 · Objective To establish an effective screening model of congenital anomalies of the kidney and urinary tract (CAKUT) using ultrasound among neonates in Shanghai, China. Design Cross-sectional study. Setting A three-level screening model for CAKUT in neonates based on the child healthcare system was established since 2010 in Minhang District, Shanghai, China.

Early detection of congenital anomalies of the kidney and ...

Transcriptome-wide based identification of miRs in ...

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6/30/2016 · The genetic cause of most congenital anomalies of the kidney and urinary tract (CAKUT) cases remains unknown, therefore the novel approaches in searching for the common disease denominators are required. miRs regulate gene expression in humans and therefore have potentially therapeutic and biomarker properties. No studies thus far have attempted to explore the miRs in …

Transcriptome-wide based identification of miRs in ...

Antibiotics Prophylaxis in Patients with CAKUT, Does It ...

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The incidence of CAKUT among patients with urinary tract infection (UTI) ranges from 25% - 55% [6] . Ring and Zobel found CAKUT in 42% of infants with UTI, with obstructive uropathy and vesicoureteral reflux (VUR) accounting for 37% and 59% of all the anomalies respectively [7] . Also, in that study 61% of infants with CAKUT had UTI [7] .

Antibiotics Prophylaxis in Patients with CAKUT, Does It ...

Genetic basis of human congenital anomalies of the kidney ...

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1/2/2018 · Genetic basis of human congenital anomalies of the kidney and urinary tract ... CAKUT, congenital anomalies of the kidney and urinary tract. ... that missense mutations are more likely to represent hypomorphic alleles with milder manifestation such as isolated CAKUT (119, 121). A study on a large cohort of CAKUT and VACTERL (vertebral anomalies

Genetic basis of human congenital anomalies of the kidney ...

Incidence and Risks of Congenital Anomalies of Kidney and ...

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Congenital anomalies of the kidney and urinary tract (CAKUT) are 1 of the major factors in young adults needing renal replacement therapy, but there is little extensive assessment of their incidence and risk factors. This study aimed to evaluate trends in the incidence of …

Incidence and Risks of Congenital Anomalies of Kidney and ...
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